YAKEEN is about Nikhil (Arjun Rampal), a young and handsome business tycoon in Himachal, married to the beautiful Simar (Priyanka Chopra), a young lady with considerable charms. Though it's happy marriage, their relationship is seemingly devoid of that closeness which represents the ideal bonding. Life takes a bizarre turn when their car plummets from a height crashing down the hillside, turning into a total wreck. Nikhil is moved in a comatose to the finest hospital and his recovery from an extremely critical state is both slow and painful. The beautiful Simar escapes relatively unscathed with minor cuts and bruises.